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DHX58

Gene

DExH-box helicase 58

HGNCHGNC:29517EnsemblENSG00000108771NCBI Gene79132
Locus: gene with protein productLocation: 17q21.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLGP2 · D11LGP2
View full nomenclature history (4)
Alias symbolsLGP2, D11LGP2
Previous namesDEXH (Asp-Glu-X-His) box polypeptide 58
Alias namesRNA helicase LGP2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Coronary Artery Disease
Psoriasis
Virus Diseases
Infections
Neuroblastoma
Zika Virus Infection
Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

DEAH-box helicasesRIG-I RNA sensor family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.