DIRAS1

Gene

DIRAS family GTPase 1

HGNCHGNC:19127 EnsemblENSG00000176490 NCBI Gene148252

Locus: gene with protein productLocation: 19p13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDi-Ras1 · GBTS1 · RIG

View full nomenclature history (7)

Alias symbolsDi-Ras1, GBTS1, RIG

Previous namesDIRAS family, GTP-binding RAS-like 1

Alias namesRas-related inhibitor of cell growth, small GTP-binding tumor suppressor 1, distinct subgroup of the Ras family member 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Leukoplakia, Oral

Carcinoma, Renal Cell

Neoplasms

Uterine Cervical Neoplasms

Glioma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

RAS type GTPase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.