Back to discover

DNMT3L

Gene

DNA methyltransferase 3 like

HGNCHGNC:2980EnsemblENSG00000142182NCBI Gene29947
Locus: gene with protein productLocation: 21q22.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMGC1090
View full nomenclature history (3)
Alias symbolsMGC1090
Previous namesDNA (cytosine-5-)-methyltransferase 3-like
Alias namescytosine-5-methyltransferase 3-like protein

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Ventricular Fibrillation
Cardiovascular Diseases
Arthritis, Rheumatoid
Carcinoma, Hepatocellular
Spermatogenic failure
Non-syndromic male infertility due to sperm motility disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

7BS C5-cytosine DNA/RNA methyltransferasesDNA/RNA methyltransferases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.