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DPM1

Gene

dolichyl-phosphate mannosyltransferase subunit 1, catalytic

HGNCHGNC:3005EnsemblENSG00000000419NCBI Gene8813
Locus: gene with protein productLocation: 20q13.13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMPDS · CDGIE
View full nomenclature history (4)
Alias symbolsMPDS, CDGIE
Previous namesdolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
Alias namesDPM synthase complex, catalytic subunit

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Dengue
Genetic Diseases, Inborn
Congenital disorder of glycosylation
SRD5A3-congenital disorder of glycosylation
Carcinoma, Hepatocellular
Prostate carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Glycosyltransferase family 2Dolichyl-phosphate mannosyltransferase subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.