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DRAM2

Gene

DNA damage regulated autophagy modulator 2

HGNCHGNC:28769EnsemblENSG00000156171NCBI Gene128338
Locus: gene with protein productLocation: 1p13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTMEM77 · MGC54289 · PRO180 · WWFQ154 · RP5-1180E21.1
View full nomenclature history (7)
Previous symbolsTMEM77
Alias symbolsMGC54289, PRO180, WWFQ154, RP5-1180E21.1
Previous namestransmembrane protein 77, DNA-damage regulated autophagy modulator 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cone rod dystrophy
Cone-rod dystrophy
Retinal Diseases
Genetic Diseases, Inborn
Macular Degeneration

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

DRAM autophagy modulator family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.