Back to discover

DROSHA

Gene

drosha ribonuclease III

HGNCHGNC:17904EnsemblENSG00000113360NCBI Gene29102
Locus: gene with protein productLocation: 5p13.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Ribonuclease 3Q9NRR4

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRNASEN · RNASE3L · Etohi2 · HSA242976 · RN3
View full nomenclature history (8)
Previous symbolsRNASEN
Alias symbolsRNASE3L, Etohi2, HSA242976, RN3
Previous namesribonuclease type III, nuclear
Alias namesdrosha, ribonuclease type III, drosha, double-stranded RNA-specific endoribonuclease

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

EndoribonucleasesMicroprocessor complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.