ENTPD4

Gene

ectonucleoside triphosphate diphosphohydrolase 4

HGNCHGNC:14573 EnsemblENSG00000197217 NCBI Gene9583

Locus: gene with protein productLocation: 8p21.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLYSAL1 · LALP70 · LAP70 · KIAA0392 · NTPDase-4 · UDPase

View full nomenclature history (7)

Previous symbolsLYSAL1

Alias symbolsLALP70, LAP70, KIAA0392, NTPDase-4, UDPase

Previous nameslysosomal apyrase-like 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hypothyroidism

Central Nervous System Neoplasms

Ependymoma

Hydrops fetalis

Ovarian carcinoma

Acquired Immunodeficiency Syndrome

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Ectonucleoside triphosphate diphosphohydrolase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.