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EPHX2

Gene

epoxide hydrolase 2

HGNCHGNC:3402EnsemblENSG00000120915NCBI Gene2053
Locus: gene with protein productLocation: 8p21.2-p21.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asABHD20 · sEH
View full nomenclature history (5)
Alias symbolsABHD20, sEH
Previous namesepoxide hydrolase 2, cytoplasmic
Alias namessoluble epoxide hydrolase, bifunctional epoxide hydrolase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Alzheimer's Disease
Smoking initiation
Lung carcinoma
Pulmonary Disease, Chronic Obstructive
Marijuana Abuse
Schizophrenia
Chronic bronchitis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Abhydrolase domain containingHAD Asp-based non-protein phosphatases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.