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ERCC3

Gene

ERCC excision repair 3, TFIIH core complex helicase subunit

HGNCHGNC:3435EnsemblENSG00000163161NCBI Gene2071
Locus: gene with protein productLocation: 2q14.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asXPB · BTF2 · RAD25 · Ssl2
View full nomenclature history (7)
Alias symbolsXPB, BTF2, RAD25, Ssl2
Previous namesexcision repair cross-complementing rodent repair deficiency, complementation group 3, excision repair cross-complementation group 3
Alias namesxeroderma pigmentosum group B complementing

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Xeroderma Pigmentosum
HIV Infections
Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Xeroderma pigmentosum complementation groupsERCC excision repair associatedGeneral transcription factor IIH complex subunitsDexD/H helicases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.