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ERCC5

Gene

ERCC excision repair 5, endonuclease

HGNCHGNC:3437EnsemblENSG00000134899NCBI Gene2073
Locus: gene with protein productLocation: 13q33.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asERCM2 · XPGC
View full nomenclature history (6)
Previous symbolsERCM2, XPGC
Previous namesxeroderma pigmentosum, complementation group G, excision repair cross-complementing rodent repair deficiency, complementation group 5, excision repair cross-complementation group 5
Alias namesCockayne syndrome

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Xeroderma Pigmentosum
Genetic Diseases, Inborn
Ovarian Neoplasms
Prostate carcinoma
Melanoma
Cutaneous melanoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Xeroderma pigmentosum complementation groupsERCC excision repair associatedRad2/XPG endonuclease family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.