FAS

Gene

Fas cell surface death receptor

HGNCHGNC:11920 EnsemblENSG00000026103 NCBI Gene355

Locus: gene with protein productLocation: 10q23.31

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asFAS1 · APT1 · TNFRSF6 · CD95 · APO-1

View full nomenclature history (8)

Previous symbolsFAS1, APT1, TNFRSF6

Alias symbolsCD95, APO-1

Previous namestumor necrosis factor receptor superfamily, member 6, Fas (TNF receptor superfamily, member 6)

Alias namesTNF receptor superfamily member 6

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Lymphoid neoplasm

Lymphoma

Neurodegenerative Diseases

Leukemia, Lymphocytic, Chronic, B-Cell

Lymphoma, Large B-Cell, Diffuse

Hypothyroidism

Genetic Diseases, Inborn

Hashimoto's Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesTumor necrosis factor receptor superfamilyDeath inducing signaling complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.

Open TargetsGene–disease associations from the Open Targets Platform.