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FXYD1

Gene

FXYD domain containing ion transport regulator 1

HGNCHGNC:4025EnsemblENSG00000266964NCBI Gene5348
Locus: gene with protein productLocation: 19q13.12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPLM
View full nomenclature history (2)
Previous symbolsPLM
Previous namesphospholemman

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Familial isolated dilated cardiomyopathy
Retinal Degeneration
Alzheimer's Disease
Carcinoma, Hepatocellular
Rett Syndrome

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

FXYD domain containing ion transport regulators

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-04-16.
Open TargetsGene–disease associations from the Open Targets Platform.