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FZD4

Gene

frizzled class receptor 4

HGNCHGNC:4042EnsemblENSG00000174804NCBI Gene8322
Locus: gene with protein productLocation: 11q14.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asEVR1 · CD344
View full nomenclature history (7)
Previous symbolsEVR1
Alias symbolsCD344
Previous namesfrizzled (Drosophila) homolog 4, exudative vitreoretinopathy 1, frizzled homolog 4 (Drosophila), frizzled 4, seven transmembrane spanning receptor, frizzled family receptor 4

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Eye Diseases
Retinal Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

G protein-coupled receptors, Class F frizzledCD molecules

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.