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G6PC2

Gene

glucose-6-phosphatase catalytic subunit 2

HGNCHGNC:28906EnsemblENSG00000152254NCBI Gene57818
Locus: gene with protein productLocation: 2q31.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asIGRP
View full nomenclature history (3)
Alias symbolsIGRP
Previous namesglucose-6-phosphatase, catalytic, 2
Alias namesislet specific glucose 6 phosphatase catalytic subunit related protein

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Glucose Metabolism Disorders
Diabetes, Gestational
Carbohydrate Metabolism, Inborn Errors
Metabolic Syndrome
Diabetes Mellitus, Type 2
Diabetic Retinopathy

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Glucose 6-phosphatases, catalytic

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-10-26.
Open TargetsGene–disease associations from the Open Targets Platform.