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G6PC3

Gene

glucose-6-phosphatase catalytic subunit 3

HGNCHGNC:24861EnsemblENSG00000141349NCBI Gene92579
Locus: gene with protein productLocation: 17q21.31

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asUGRP
View full nomenclature history (3)
Alias symbolsUGRP
Previous namesglucose 6 phosphatase, catalytic, 3
Alias namesUbiquitous glucose-6-phosphatase catalytic subunit-related protein

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Severe congenital neutropenia
Genetic Diseases, Inborn
Neurodegenerative Diseases
Infections
Isolated agammaglobulinemia
Glioblastoma
Autosomal agammaglobulinemia

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Glucose 6-phosphatases, catalytic

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-10-26.
Open TargetsGene–disease associations from the Open Targets Platform.