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GCK

Gene

glucokinase

HGNCHGNC:4195EnsemblENSG00000106633NCBI Gene2645
Locus: gene with protein productLocation: 7p13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMODY2 · HK4 · HKIV
View full nomenclature history (6)
Previous symbolsMODY2
Alias symbolsHK4, HKIV
Previous namesmaturity onset diabetes of the young 2, glucokinase (hexokinase 4)
Alias nameshexokinase 4

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

MODY
Diabetes Mellitus, Type 2
Diabetes Mellitus
Permanent neonatal diabetes mellitus

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Hexokinase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-05-14.
Open TargetsGene–disease associations from the Open Targets Platform.