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GP1BB

Gene

glycoprotein Ib platelet subunit beta

HGNCHGNC:4440EnsemblENSG00000203618NCBI Gene2812
Locus: gene with protein productLocation: 22q11.21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCD42c · GPIbbeta
View full nomenclature history (4)
Alias symbolsCD42c, GPIbbeta
Previous namesglycoprotein Ib (platelet), beta polypeptide
Alias namesplatelet glycoprotein Ib beta chain

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Autosomal dominant macrothrombocytopenia
Thrombocytopenia 4

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesHuman platelet antigens

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.