GRIA3

Gene

glutamate ionotropic receptor AMPA type subunit 3

HGNCHGNC:4573 EnsemblENSG00000125675 NCBI Gene2892

Locus: gene with protein productLocation: Xq25

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Glutamate receptor 3P42263

Protein · therapeutic target

Clinically validated target · 2 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asGLUR3 · GluA3 · GLURC · MRX94 · GluR-3 · GluR-C · GluR-K3 · iGluR3

View full nomenclature history (11)

Previous symbolsGLUR3

Alias symbolsGluA3, GLURC, MRX94, GluR-3, GluR-C, GluR-K3, iGluR3

Previous namesglutamate receptor, ionotrophic, AMPA 3

Alias namesGlutamate receptor 3, AMPA receptor subunit GluA3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Epilepsy

Migraine Disorders

Alcoholism

Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Glutamate ionotropic receptor AMPA type subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.