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GRIN2C

Gene

glutamate ionotropic receptor NMDA type subunit 2C

HGNCHGNC:4587EnsemblENSG00000161509NCBI Gene2905
Locus: gene with protein productLocation: 17q25.1

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Glutamate receptor ionotropic, NMDA 2CQ14957

Protein · therapeutic target

Clinically validated target · 13 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asNMDAR2C · GluN2C · NR2C
View full nomenclature history (4)
Previous symbolsNMDAR2C
Alias symbolsGluN2C, NR2C
Previous namesglutamate receptor, ionotropic, N-methyl D-aspartate 2C

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Alzheimer's Disease
Parkinson's Disease
Depressive Disorder
Major depressive disorder
Alcoholism

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Glutamate ionotropic receptor NMDA type subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-07-27.
Open TargetsGene–disease associations from the Open Targets Platform.