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GTF2H4

Gene

general transcription factor IIH subunit 4

HGNCHGNC:4658EnsemblENSG00000213780NCBI Gene2968
Locus: gene with protein productLocation: 6p21.33

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTFB2 · TFIIH · P52
View full nomenclature history (5)
Alias symbolsTFB2, TFIIH, P52
Previous namesgeneral transcription factor IIH, polypeptide 4 (52kD subunit), general transcription factor IIH, polypeptide 4, 52kDa

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

HIV Infections
Xeroderma Pigmentosum
Macular Degeneration
Arthritis, Rheumatoid
Ischemia
Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Nucleotide excision repairGeneral transcription factor IIH complex subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.