H2BC4

Gene

H2B clustered histone 4

HGNCHGNC:4757 EnsemblENSG00000180596 NCBI Gene8347

Locus: gene with protein productLocation: 6p22.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asH2BFL · HIST1H2BC · H2B/l · H2B.1

View full nomenclature history (8)

Previous symbolsH2BFL, HIST1H2BC

Alias symbolsH2B/l, H2B.1

Previous nameshistone cluster 1 H2B family member c, H2B histone family, member L, histone 1, H2bc, histone cluster 1, H2bc

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Communicable Diseases

Virus Diseases

Alzheimer's disease type 1

Cardiomyopathies

Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

H2B histones

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.