HACD1

Gene

3-hydroxyacyl-CoA dehydratase 1

HGNCHGNC:9639 EnsemblENSG00000165996 NCBI Gene9200

Locus: gene with protein productLocation: 10p12.33

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPTPLA · CAP

View full nomenclature history (5)

Previous symbolsPTPLA

Alias symbolsCAP

Previous namesprotein tyrosine phosphatase-like (proline instead of catalytic arginine), member a

Alias namescementum attachment protein, Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Congenital fiber-type disproportion myopathy

Genetic Diseases, Inborn

Retinitis Pigmentosa

Cone rod dystrophy

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

3-hydroxyacyl-CoA dehydratase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.