HCST

Gene

hematopoietic cell signal transducer

HGNCHGNC:16977 EnsemblENSG00000126264 NCBI Gene10870

Locus: gene with protein productLocation: 19q13.12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPIK3AP · DAP10 · DKFZP586C1522 · KAP10

View full nomenclature history (7)

Previous symbolsPIK3AP

Alias symbolsDAP10, DKFZP586C1522, KAP10

Previous namesphosphoinositide-3-kinase adaptor protein

Alias namesDNAX-activation protein 10, kinase assoc pro of ~10kDa

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neoplasms

Melorheostosis

bone Paget's disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.