HMOX1

Gene

heme oxygenase 1

HGNCHGNC:5013 EnsemblENSG00000100292 NCBI Gene3162

Locus: gene with protein productLocation: 22q12.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Heme oxygenase 1P09601

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asbK286B10 · HO-1

View full nomenclature history (3)

Alias symbolsbK286B10, HO-1

Previous namesheme oxygenase (decycling) 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Amyloidosis

Neurodegenerative Diseases

Cystic Fibrosis

Pulmonary Disease, Chronic Obstructive

Gastrointestinal Diseases

Neoplasms

Acute Kidney Injury

Alzheimer's Disease

Carcinoma, Hepatocellular

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Heme oxygenase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.