HNF1B

Gene

HNF1 homeobox B

HGNCHGNC:11630 EnsemblENSG00000275410 NCBI Gene6928

Locus: gene with protein productLocation: 17q12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTCF2 · LFB3 · VHNF1 · HNF1beta · MODY5 · HNF1β

View full nomenclature history (8)

Previous symbolsTCF2

Alias symbolsLFB3, VHNF1, HNF1beta, MODY5, HNF1β

Previous namestranscription factor 2, hepatic; LF-B3; variant hepatic nuclear factor

Alias nameshepatocyte nuclear factor 1 beta

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Diabetes Mellitus, Type 2

MODY

Diabetes Mellitus

Prostate carcinoma

Neurodegenerative Diseases

Carcinoma, Renal Cell

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

HNF class homeoboxes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.