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HNF4A

Gene

hepatocyte nuclear factor 4 alpha

HGNCHGNC:5024EnsemblENSG00000101076NCBI Gene3172
Locus: gene with protein productLocation: 20q13.12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTCF14 · MODY · MODY1 · NR2A1 · HNF4
View full nomenclature history (5)
Previous symbolsTCF14, MODY, MODY1
Alias symbolsNR2A1, HNF4

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

MODY
Diabetes Mellitus, Type 2
Diabetes Mellitus
Cholelithiasis
Gallstones
Gastrointestinal disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

MicroRNA protein coding host genesHepatocyte nuclear factor 4 family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.