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HSD17B11

Gene

hydroxysteroid 17-beta dehydrogenase 11

HGNCHGNC:22960EnsemblENSG00000198189NCBI Gene51170
Locus: gene with protein productLocation: 4q22.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDHRS8 · RetSDR2 · 17-BETA-HSD11 · 17-BETA-HSDXI · PAN1B · SDR16C2
View full nomenclature history (10)
Previous symbolsDHRS8
Alias symbolsRetSDR2, 17-BETA-HSD11, 17-BETA-HSDXI, PAN1B, SDR16C2
Previous namesdehydrogenase/reductase (SDR family) member 8, hydroxysteroid (17-beta) dehydrogenase 11
Alias namesretinal short-chain dehydrogenase/reductase 2, short chain dehydrogenase/reductase family 16C, member 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Nephritis
Hypertension
Essential Hypertension
Hypertriglyceridemia
Gout
Nephrotic Syndrome

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Short chain dehydrogenase/reductase superfamily

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.