Back to discover

HTR1B

Gene

5-hydroxytryptamine receptor 1B

HGNCHGNC:5287EnsemblENSG00000135312NCBI Gene3351
Locus: gene with protein productLocation: 6q14.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asS12 · 5-HT1B · HTR1D2 · 5-HT1DB
View full nomenclature history (6)
Alias symbolsS12, 5-HT1B, HTR1D2, 5-HT1DB
Previous names5-hydroxytryptamine (serotonin) receptor 1B, 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Migraine Disorders
Schizophrenia
Major depressive disorder
Smoking initiation
Depressive Disorder
Psychotic disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

5-hydroxytryptamine receptors, G protein-coupled

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.