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IDH3A

Gene

isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha

HGNCHGNC:5384EnsemblENSG00000166411NCBI Gene3419
Locus: gene with protein productLocation: 15q25.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

View full nomenclature history (8)
Previous namesisocitrate dehydrogenase 3 (NAD+) alpha, isocitrate dehydrogenase (NAD(+)) 3 alpha
Alias namesNAD+-specific ICDH, H-IDH alpha, isocitric dehydrogenase, isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, NAD(H)-specific isocitrate dehydrogenase alpha subunit, isocitrate dehydrogenase (NAD+) alpha chain

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Retinitis Pigmentosa
Neurodegenerative Diseases
Cone rod dystrophy
Leber Congenital Amaurosis
Color Vision Defects

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Isocitrate dehydrogenases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.