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IDUA

Gene

alpha-L-iduronidase

HGNCHGNC:5391EnsemblENSG00000127415NCBI Gene3425
Locus: gene with protein productLocation: 4p16.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMPS1 · MPSI
View full nomenclature history (4)
Alias symbolsMPS1, MPSI
Previous namesiduronidase, alpha-L-
Alias namesmucopolysaccharidosis type I

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Mucopolysaccharidosis I
Genetic Diseases, Inborn
Fractures, Bone

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Glycoside hydrolase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.