IL17A

Gene

interleukin 17A

HGNCHGNC:5981 EnsemblENSG00000112115 NCBI Gene3605

Locus: gene with protein productLocation: 6p12.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Interleukin-17AQ16552

Protein · therapeutic target

Clinically validated target · 3 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCTLA8 · IL17 · IL-17A · IL-17

View full nomenclature history (6)

Previous symbolsCTLA8, IL17

Alias symbolsIL-17A, IL-17

Previous namesinterleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

Alias namescytotoxic T-lymphocyte-associated protein 8

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Psoriasis

Psoriasis vulgaris

Arthritis, Psoriatic

Spondylitis, Ankylosing

Immune System Diseases

Hidradenitis Suppurativa

Arthritis, Rheumatoid

Arthritis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Interleukins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.