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IL22

Gene

interleukin 22

HGNCHGNC:14900EnsemblENSG00000127318NCBI Gene50616
Locus: gene with protein productLocation: 12q15

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Interleukin-22Q9GZX6

Protein · therapeutic target

Clinical-stage target · 1 candidate in clinical development

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asILTIF · IL-21 · zcyto18 · IL-TIF · IL-D110 · TIFa · TIFIL-23 · IL-22 · MGC79382 · MGC79384
View full nomenclature history (11)
Alias symbolsILTIF, IL-21, zcyto18, IL-TIF, IL-D110, TIFa, TIFIL-23, IL-22, MGC79382, MGC79384
Alias namesIL-10-related T-cell-derived inducible factor

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Dermatitis, Atopic
Neoplasms
Dermatitis
Arthritis, Rheumatoid
Psoriasis
Infections

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Interleukins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.