IL3RA

Gene

interleukin 3 receptor subunit alpha

HGNCHGNC:6012 EnsemblENSG00000185291 NCBI Gene3563

Locus: gene with protein productLocation: Xp22.33 and Yp11.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Interleukin-3 receptor subunit alphaP26951

Protein · therapeutic target

Clinically validated target · 1 approved medicine against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCD123

View full nomenclature history (2)

Alias symbolsCD123

Previous namesinterleukin 3 receptor, alpha (low affinity)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Leukemia, Myeloid, Acute

Neoplasms

Lymphoma

Neurodegenerative Diseases

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Myelodysplastic syndrome

Leukemia

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesInterleukin receptorsPseudoautosomal region 1

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-10-22.

Open TargetsGene–disease associations from the Open Targets Platform.