IMPDH1

Gene

inosine monophosphate dehydrogenase 1

HGNCHGNC:6052 EnsemblENSG00000106348 NCBI Gene3614

Locus: gene with protein productLocation: 7q32.1

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Inosine-5'-monophosphate dehydrogenase 1P20839

Protein · therapeutic target

Clinically validated target · 8 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRP10 · sWSS2608 · LCA11

View full nomenclature history (5)

Previous symbolsRP10

Alias symbolssWSS2608, LCA11

Previous namesretinitis pigmentosa 10 (autosomal dominant), IMP (inosine 5'-monophosphate) dehydrogenase 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Retinitis Pigmentosa

Retinitis pigmentosa 10

Leber Congenital Amaurosis

Leber congenital amaurosis 11

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Inosine monophosphate dehydrogenase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.