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INS

Gene

insulin

HGNCHGNC:6081EnsemblENSG00000254647NCBI Gene3630
Locus: gene with protein productLocation: 11p15.5

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asIDDM2 · IDDM1
View full nomenclature history (3)
Previous symbolsIDDM2, IDDM1
Previous namesinsulin-dependent diabetes mellitus 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

MODY
Diabetes Mellitus, Type 1
Permanent neonatal diabetes mellitus
Diabetes Mellitus
Diabetes Mellitus, Type 2

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

NeuropeptidesInsulin family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.