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ITK

Gene

IL2 inducible T cell kinase

HGNCHGNC:6171EnsemblENSG00000113263NCBI Gene3702
Locus: gene with protein productLocation: 5q33.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asEMT · PSCTK2 · LYK
View full nomenclature history (5)
Alias symbolsEMT, PSCTK2, LYK
Previous namesIL2-inducible T-cell kinase, IL2 inducible T-cell kinase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Carcinoma, Renal Cell
Sarcoma
Hodgkin's Disease
Severe Combined Immunodeficiency
Soft tissue sarcoma
Hypothyroidism
Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Pleckstrin homology domain containingSH2 domain containingTec family tyrosine kinases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.