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JUP

Gene

junction plakoglobin

HGNCHGNC:6207EnsemblENSG00000173801NCBI Gene3728
Locus: gene with protein productLocation: 17q21.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCTNNG · DP3 · PDGB · PKGB · DPIII · PG
View full nomenclature history (10)
Previous symbolsCTNNG
Alias symbolsDP3, PDGB, PKGB, DPIII, PG
Previous namescatenin (cadherin-associated protein), gamma 80kDa
Alias namesgamma catenin, plakoglobin, desmosomal protein 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Arrhythmogenic Right Ventricular Dysplasia
Cardiomyopathy, Dilated
Cardiomyopathies

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Armadillo repeat containingBeta catenins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-06-19.
Open TargetsGene–disease associations from the Open Targets Platform.