KCNA1

Gene

potassium voltage-gated channel subfamily A member 1

HGNCHGNC:6218 EnsemblENSG00000111262 NCBI Gene3736

Locus: gene with protein productLocation: 12p13.32

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Potassium voltage-gated channel subfamily A member 1Q09470

Protein · therapeutic target

Clinically validated target · 5 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asAEMK · Kv1.1 · RBK1 · HUK1 · MBK1

View full nomenclature history (6)

Previous symbolsAEMK

Alias symbolsKv1.1, RBK1, HUK1, MBK1

Previous namespotassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Multiple Sclerosis

Myasthenia Gravis

Congenital myasthenic syndromes

Genetic Diseases, Inborn

Familial paroxysmal ataxia

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Potassium voltage-gated channelsBTB domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.