KCNB1

Gene

potassium voltage-gated channel subfamily B member 1

HGNCHGNC:6231 EnsemblENSG00000158445 NCBI Gene3745

Locus: gene with protein productLocation: 20q13.13

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Potassium voltage-gated channel subfamily B member 1Q14721

Protein · therapeutic target

Clinically validated target · 5 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asKv2.1

View full nomenclature history (2)

Alias symbolsKv2.1

Previous namespotassium voltage-gated channel, Shab-related subfamily, member 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Undetermined early-onset epileptic encephalopathy

Genetic developmental and epileptic encephalopathy

Genetic Diseases, Inborn

Congenital myasthenic syndromes

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Potassium voltage-gated channelsBTB domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.