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KCNH5

Gene

potassium voltage-gated channel subfamily H member 5

HGNCHGNC:6254EnsemblENSG00000140015NCBI Gene27133
Locus: gene with protein productLocation: 14q23.2

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Voltage-gated delayed rectifier potassium channel KCNH5Q8NCM2

Protein · therapeutic target

Clinically validated target · 5 approved medicines against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asKv10.2 · H-EAG2 · eag2 · hEAG2
View full nomenclature history (6)
Alias symbolsKv10.2, H-EAG2, eag2, hEAG2
Previous namespotassium voltage-gated channel, subfamily H (eag-related), member 5
Alias namesether-a-go-go 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Myasthenia Gravis
early-infantile DEE
Genetic developmental and epileptic encephalopathy

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Potassium voltage-gated channelsPAS domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.