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KCNK6

Gene

potassium two pore domain channel subfamily K member 6

HGNCHGNC:6281EnsemblENSG00000099337NCBI Gene9424
Locus: gene with protein productLocation: 19q13.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asK2p6.1 · TWIK-2
View full nomenclature history (4)
Alias symbolsK2p6.1, TWIK-2
Previous namespotassium channel, subfamily K, member 6, potassium channel, two pore domain subfamily K, member 6

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Autoimmune disorder of central nervous system
Diabetic Ketoacidosis
Breast Neoplasms
Atrial Fibrillation
Moyamoya disease with early-onset achalasia

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Potassium two pore domain channel subfamily K

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.