KDM5C

Gene

lysine demethylase 5C

HGNCHGNC:11114 EnsemblENSG00000126012 NCBI Gene8242

Locus: gene with protein productLocation: Xp11.22

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSMCX · JARID1C · MRX13 · DXS1272E · XE169

View full nomenclature history (10)

Previous symbolsSMCX, JARID1C, MRX13

Alias symbolsDXS1272E, XE169

Previous nameslysine (K)-specific demethylase 5C, Jumonji, AT rich interactive domain 1C (RBP2-like), Smcy homolog, X-linked (mouse), jumonji, AT rich interactive domain 1C, mental retardation, X-linked 13

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Carcinoma, Renal Cell

Genetic Diseases, Inborn

Colorectal adenocarcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

PHD finger proteinsAT-rich interaction domain containingLysine demethylasesMicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.