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LINGO2

Gene

leucine rich repeat and Ig domain containing 2

HGNCHGNC:21207EnsemblENSG00000174482NCBI Gene158038
Locus: gene with protein productLocation: 9p21.2-p21.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLRRN6C · LERN3
View full nomenclature history (3)
Previous symbolsLRRN6C
Alias symbolsLERN3
Previous namesleucine rich repeat neuronal 6C

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Obesity disorder
Diabetes Mellitus, Type 2
Diabetes Mellitus
Overnutrition
Restless Legs Syndrome
Smoking initiation
Pre-Eclampsia
Migraine Disorders
Graves' Disease

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

I-set domain containingMicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.