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LIPA

Gene

lipase A, lysosomal acid type

HGNCHGNC:6617EnsemblENSG00000107798NCBI Gene3988
Locus: gene with protein productLocation: 10q23.31

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLAL · CESD
View full nomenclature history (6)
Alias symbolsLAL, CESD
Previous nameslipase A, lysosomal acid, cholesterol esterase
Alias namesWolman disease, lysosomal acid lipase, sterol esterase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Coronary Artery Disease
Myocardial Infarction
Cardiovascular Diseases
Cholestasis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Lipases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.