LMAN1

Gene

lectin, mannose binding 1

HGNCHGNC:6631 EnsemblENSG00000074695 NCBI Gene3998

Locus: gene with protein productLocation: 18q21.32

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asF5F8D · MR60 · ERGIC-53 · ERGIC53 · gp58 · MCFD1 · FMFD1

View full nomenclature history (10)

Previous symbolsF5F8D

Alias symbolsMR60, ERGIC-53, ERGIC53, gp58, MCFD1, FMFD1

Previous namescoagulation factor V-factor VIII combined deficiency, lectin, mannose-binding, 1

Alias namesendoplasmic reticulum-golgi intermediate compartment protein 53

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Retinitis Pigmentosa

Neurodegenerative Diseases

Respiratory Tract Infections

Genetic Diseases, Inborn

Hypothyroidism

Hemophilia A

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.