LMNA

Gene

lamin A/C

HGNCHGNC:6636 EnsemblENSG00000160789 NCBI Gene4000

Locus: gene with protein productLocation: 1q22

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLMN1 · CMD1A · LGMD1B · PRO1 · LMNL1 · HGPS · MADA

View full nomenclature history (13)

Previous symbolsLMN1, CMD1A, LGMD1B, PRO1, LMNL1

Alias symbolsHGPS, MADA

Previous namescardiomyopathy, dilated 1A (autosomal dominant), limb girdle muscular dystrophy 1B (autosomal dominant), progeria 1 (Hutchinson-Gilford type), lamin A/C-like 1

Alias namesmandibuloacral dysplasia type A, progerin

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cardiomyopathy, Dilated

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Lamins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-04-21.

Open TargetsGene–disease associations from the Open Targets Platform.