LSM2

Gene

LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated

HGNCHGNC:13940 EnsemblENSG00000204392 NCBI Gene57819

Locus: gene with protein productLocation: 6p21.33

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC6orf28 · G7b · YBL026W

View full nomenclature history (5)

Previous symbolsC6orf28

Alias symbolsG7b, YBL026W

Previous namesLSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae), chromosome 6 open reading frame 28

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Central Nervous System Neoplasms

Glioma

Neoplasms

Glioblastoma

Pulmonary Disease, Chronic Obstructive

Guillain-Barre Syndrome

Proximal spinal muscular atrophy

Cutaneous melanoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

LSm proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.