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LZTR1

Gene

leucine zipper like post translational regulator 1

HGNCHGNC:6742EnsemblENSG00000099949NCBI Gene8216
Locus: gene with protein productLocation: 22q11.21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLZTR-1 · BTBD29
View full nomenclature history (4)
Alias symbolsLZTR-1, BTBD29
Previous namesleucine-zipper-like transcriptional regulator 1, leucine zipper like transcription regulator 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Noonan syndrome
RASopathy
Inherited cancer-predisposing syndrome
Neoplastic Syndromes, Hereditary

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

BTB domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-13.
Open TargetsGene–disease associations from the Open Targets Platform.