MARK2

Gene

microtubule affinity regulating kinase 2

HGNCHGNC:3332 EnsemblENSG00000072518 NCBI Gene2011

Locus: gene with protein productLocation: 11q13.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asEMK1 · PAR-1 · Par1b · PAR-1B

View full nomenclature history (10)

Previous symbolsEMK1

Alias symbolsPAR-1, Par1b, PAR-1B

Previous namesELKL motif kinase, MAP/microtubule affinity-regulating kinase 2

Alias namesELKL motif kinase 1, serine/threonine kinase, protein-serine/threonine kinase, Ser/Thr protein kinase PAR-1B

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Autism Spectrum Disorder

Neurodegenerative Diseases

Pancreatic adenocarcinoma

Neurodevelopmental Disorders

Attention Deficit Disorder with Hyperactivity

Autistic Disorder

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Microtubule affinity regulating kinases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.