MCCC1

Gene

methylcrotonyl-CoA carboxylase subunit 1

HGNCHGNC:6936 EnsemblENSG00000078070 NCBI Gene56922

Locus: gene with protein productLocation: 3q27.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMCCA · MCCCα

View full nomenclature history (6)

Alias symbolsMCCA, MCCCα

Previous namesmethylcrotonoyl-Coenzyme A carboxylase 1 (alpha), methylcrotonoyl-CoA carboxylase 1

Alias namesmethylcrotonoyl-CoA carboxylase alpha, 3-methylcrotonyl-CoA carboxylase biotin containing subunit

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic Diseases, Inborn

Parkinson's Disease

Neurodegenerative Diseases

Lewy Body Disease

Retinitis Pigmentosa

Cone rod dystrophy

Early-onset non-syndromic cataract

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Methylcrotonyl-CoA carboxylase subunitsATP-grasp fold containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.